Withdrawal from stimulant drugs (cocaine, MDMA, amphetamines) does not cause huge physical side effects rather the effects are psychological. The major effects of long term stimulant use are greatly elevated levels of oxidative stress resulting in a decline in cognitive functions. NAD+ therapy will help to reduce these effects as well as promoting the restoration of normal transmitter balance.

Practitioners hope to work within National Institute for Health and Care Excellence (NICE) guidelines to withdraw patients from tranquillisers at a pace suited to each individual. They believe tailor-made protocols could help some withdraw in weeks rather than months and years.